I was watching "The Zanti Misfits" episode of the classic Outer Limits TV show the other day. You remember that one, right? It's the one with the little (well, hand size) bug/spider-like aliens with HUMAN faces.
The "misfits" are actually criminals from another world, their sentence exile on Earth. Well, of course they run afoul of the military and in one scene the Zanti overrun an Air Force command center. PANEDEMONIUM ENSUES! One dude, an MP-type runs off-screen, his .45 blasting away, and a second later comes crashing down the stairs covered in Zanti!
These folks in "Zanti" were in the fight of their lives against some pretty rudimentary special effects (the Misfits were done with some limited stop motion animation, or, in most shots, with a rubber dummy prop) and they performed with complete conviction, as if acting opposite Marlon Brando and Laurence Olivier instead of rubber bugs. My point being that science fiction shows and movies often have better acting than their more traditional non-genre cousins. In other words, I'd like to see someone like Dr. McDreamy on Grey's Anatomy fall down a flight of stairs covered in Zanti Misfits and make you believe it!
If they could, I smell Emmy Awards.